Introduction to Ancon's Technology Areas
ANCON has developed and patented leading-edge technologies for the measurement of trace quantities of Volatile Organic Compounds (VOCs) in gaseous media. This represents a platform of technologies with applications in many fields. To date Ancon has concentrated on applications in the Security and Healthcare sectors.
Ancon has four significant groups of proprietary technologies which offer significant performance advantages compared with alternative technologies. Each of the technologies can either be integrated separately with a range of other technologies or integrated with other Ancon technologies to form a complete analysis system. The technologies are:
- Vapour Extraction Device (VED)
- Anisotropic Diffusion Mobility Analyser (ADMA)
- Nanotechnology Molecular Tagging (NMT)
- Machine Learning Biomarker Analysis (MLBA)
Read more below.
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Vapour Extraction Device (VED - patent pending)
Atmospheric aerosol particles background aerosols, dust particles and sample particles are drawn into the system. Yellow target sample spheres are vapourised and directed to the vapour analysing device (e.g. ADMA) Residual aerosol particles ejected from the system, minimising the risk of system blockage.
Anisotropic Diffusion Mobility Analyser (ADMA- Patent Granted)
ADMA is a novel and conceptually different way of improving ion selection and increasing specificity by the use of geometry, electric fields and flow rates to narrow ion trajectories. This suppresses the effects of Brownian diffusion resulting in an ion selection system with exceptionally high resolving power.
The dimensions of the ion separation zone are 2mm (length) x 3mm (width) x 5mm (length). Ions are separated spatially so ADMA can function as a scanning device producing a spectrum, or as an ion filter, producing a constant stream of selected ions.
Nanotechnology Molecular Tagging (NMT- Patent Granted)
NMT works by “amplifying” the physical volume of the ionized target molecules with specially generated nano-tags, such that ions of interest become a billion times their original volume. Tagged ions can then be counted on an individual basis with a laser optical tagged ion counter. The combination of ion cloud control, and the ability to count single target ions enables outstanding resolution and groundbreaking sensitivity
Benefits of NMT Technology:
Sensitivities one thousand times better than state-of-the-art technologies have been measured. Trace concentrations of VOCs have been measured at PPT and PPQ levels. In security this would support non-contact and earlier detection of threat materials. In healthcare, the detection of earlier stages of disease.
Machine Learning Biomarker Analysis (MLBA)
Ancon has developed a powerful proprietary machine learning software, MLBA (Machine learning Biomarker analysis), to rapidly detect patterns of volatile organic compounds (VOCs). VOCs in exhaled breath or headspace from blood, urine, sweat or saliva bear the fingerprints of metabolic and biophysical processes going on in the human body. These can be indicators of infection and disease (specifically or in pattern).
To date, we have combined Ancon’s proprietary MLBA with the breath spectra produced from a GC-IMS (G.A.S mbH). The test procedure is non-invasive, simple and streamlined. Exhaled breath, containing VOCs, is collected via a disposable mouthpiece into a sample tube which is then placed into a desktop GC-IMS.